<p>Vascular Diseases In Patients With Chronic Myeloproliferative Neoplasms – Impact Of Comorbidity</p>
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چکیده
منابع مشابه
JAK2 Exon 14 Deletion in Patients with Chronic Myeloproliferative Neoplasms
BACKGROUND The JAK2 V617F mutation in exon 14 is the most common mutation in chronic myeloproliferative neoplasms (MPNs); deletion of the entire exon 14 is rarely detected. In our previous study of >10,000 samples from patients with suspected MPNs tested for JAK2 mutations by reverse transcription-PCR (RT-PCR) with direct sequencing, complete deletion of exon 14 (Deltaexon14) constituted <1% of...
متن کاملMulticenter Retrospective Analysis of Turkish Patients with Chronic Myeloproliferative Neoplasms
OBJECTIVE Chronic myeloproliferative neoplasms (CMPNs) that include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are Philadelphia-negative malignancies characterized by a clonal proliferation of one or several lineages. The aim of this report was to determine the demographic features, disease characteristics, treatment strategies, and survival rates of...
متن کاملClinical Features of 294 Turkish Patients with Chronic Myeloproliferative Neoplasms
OBJECTIVE Myeloproliferative neoplasms (MPNs) share common clonal stem cells but show significant differences in their clinical courses. The aim of this retrospective study was to evaluate thrombotic and hemorrhagic complications, JAK2 status, gastrointestinal and cardiac changes, treatment modalities, and survival in MPNs in Turkish patients. MATERIALS AND METHODS Medical files of 294 patien...
متن کاملPhiladelphia-negative chronic myeloproliferative neoplasms
Chronic myeloproliferative diseases without the Philadelphia chromosome marker (Ph-), although first described 60 years ago, only became the subject of interest after the turn of the millennium. In 2001, the World Health Organization (WHO) defined the classification of this group of diseases and in 2008 they were renamed myeloproliferative neoplasms based on morphological, cytogenetic and molec...
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ژورنال
عنوان ژورنال: Clinical Epidemiology
سال: 2019
ISSN: 1179-1349
DOI: 10.2147/clep.s216787